Upstream development

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Drive process robustness and higher yields with data
you can trust

Achieving optimal cell growth and product yield requires precise control over culture conditions, media composition and bioreactor parameters. Yet fragmented data and manual reporting delay real-time process monitoring and optimization. Without access to reliable data, variability across batches, from pH shifts to equipment inconsistencies, can compromise cell viability and protein expression.

IDBS Polar provides a unified platform for data capture and analysis, bringing experiment and run data together with context while integrating with laboratory instruments for seamless connectivity. This delivers real-time visibility into critical parameters, enabling robust process development and confident scale-up—ensuring reliable, high-quality outcomes every time.

0
hrs

Scientists could save 200 hours on report generation in a year by going paperless with IDBS Polar*

See how IDBS Polar supports scientists in the laboratory loop from planning to execution to actionable insights

Planning, execution, integration

Capture experiment & process data

1 Capturing Data

Capture experiment, inventory and process data in real time to maintain integrity. Apply business rules for exceptions and ensure accurate tracking at execution.

Integrate with equipment

2 Integrating Instrument Data

Import structured results from instruments directly into experiment records. Data is automatically organized, linked and stored with full context for seamless integration.

Define traceable sampling plans

3 Planning Sampling Schedules

Maintain seamless data flow between bioreactors, cultures and samples, ensuring full visibility into which culture is tested under specific conditions, in which vessel and its performance.

Data aggregation + alignment

Connect planning, analysis & results

4 Connecting Planning To Analysis

Integrate sampling schedules with experiments. Generate requests that become work orders for full connectivity from planning through collection, analysis and results.

Standardize nomenclature & terminology

5 Standardizing Terminology

Use reusable templates and a central catalog to standardize workflows, reports and pick lists—ensuring consistency, saving time and improving quality across runs.

Connect bioreactors, runs & events

6 Reviewing Run Data

Review bioreactor runs for missing details before finalizing records. Filter by key parameters and export to CSV for a connected flow from execution to review to insight.

Insights that drive decisions

Compare growth curves

7 Comparing Growth Curves

Analyze data in real time with side-by-side growth curve comparisons and key metrics to assess culture performance. Export charts for audits, CAPA analysis and reporting.

Compare runs across scales

8 Comparing Scales

Compare runs across scales, highlight values, apply Nelson rules to detect trends and trace runs origins for real-time control and complete process context.

Maintain links between bioreactors & samples

9 Viewing Relationships

Use harmonized data models to link vessels, locations, cultures and samples with parent-child genealogy—or work with IDBS experts to configure models for your needs.

Learn more about Polar

IDBS Polar development applications

Cell line development
Downstream processing
Process characterization & tech transfer

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Join our customers on the road to faster innovation

Insmed
Pierre Fabre
Sarepta
Nutricia
Lonza
Inventiva
Chugai
Apellis
3B Pharmaceuticals
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*Customer data on file at IDBS. This result was originally obtained using IDBS E-WorkBook; IDBS Polar delivers the same or higher gains as IDBS E-WorkBook in a like-for-like implementation, with added value from advanced analytics, AI/ML and reporting.