IDBS Blog | 22nd August 2016

How Concentrated Are Your Reactions?

Since the release of the E‑WorkBook 10.1.2 Chemistry ELN, we have been busy augmenting the core features of the stoichiometry table. One of the enhancements we have recently implemented is the calculations of solvent concentration, with the ability to determine the molarity but also the solvent volumes of a reaction. Whilst molarity is an easily understood concept, the solvent volume measure provides an easier ratio of the quantity of solvent required per gram of reagent, which is a useful factor to consider when scaling a reaction.

Concentration is an important factor in a synthetic reaction, as it not only directly affects the rate of the reaction, but also the formation of impurities and side-products. Many discovery chemists typically run more dilute reactions to achieve a cleaner end result. Conversely, a process chemist may deliberately run the reaction in a more concentrated solution because of the practical size of equipment required. This also forces the formation of impurities to determine an appropriate purification strategy.

We believe this additional data will help to improve the reproducibility of experiments and to ensure that experiments scale with the desired outcome.

About IDBSContact us

More news

IDBS Joins BioPhorum

IDBS, a leading R&D technology and solutions provider and Tableau, the world’s leading analytics platform, announced a strategic partnership to integrate Tableau into the IDBS suite of products. The collaboration will be based on embedding Tableau’s visual and analytics capabilities into the IDBS product offerings.

Read more

i3 2021 On Demand

i3 our premier annual customer event where we bring together science, IT and R&D business leaders to share ideas, create new insights and advance innovation and this year we went virtual. During i3 you will gain insights from your peers…

Read more